Mouse models of porcine circovirus 2 infection
نویسندگان
چکیده
منابع مشابه
Porcine Circovirus PCV-2
Porcine circovirus type 2 (PCV2) is considered by most to be the etiologic agent of postweaning multisystemic wasting syndrome (PMWS), but it is also found in association with numerous other conditions. These conditions include porcine dermatitis and nephropathy syndrome (PDNS), porcine respiratory disease complex (PRDC), congenital tremors (CT) type AII, reproductive failure and enteritis. Alt...
متن کاملInhibition of Endosomal - Lysosomal System Acidification 1 Enhances Porcine Circovirus 2 Infection of Porcine
INHIBITION OF ENDOSOMAL-LYSOSOMAL SYSTEM ACIDIFICATION 1 ENHANCES PORCINE CIRCOVIRUS 2 INFECTION OF PORCINE 2 EPITHELIAL CELLS 3 4 Gerald Misinzo, Peter L. Delputte and Hans J. Nauwynck 5 6 Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 7 133, 9820 Merelbeke, Belgium 8 9 Shortened running title: blocking cell’s acidification enhances PCV2 infection 10 11...
متن کاملInhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells.
Recently, Misinzo et al. (G. Misinzo, P. Meerts, M. Bublot, J. Mast, H. M. Weingartl, and H. J. Nauwynck, J. Gen. Virol. 86:2057-2068, 2005) reported that inhibiting endosome-lysosome system acidification reduced porcine circovirus 2 (PCV2) infection of monocytic 3D4/31 cells. The present study examined the effect of inhibiting endosome-lysosome system acidification in epithelial cells, since e...
متن کاملImmunology of porcine circovirus type 2 (PCV2).
The emergence of porcine circovirus type 2 (PCV2) associated diseases and particularly postweaning multisystemic wasting syndrome (PMWS) was a shock for the swine industry and formulated a considerable challenge for researchers in the area of viral immunology in swine. The unique features of PMWS of which emaciation and lymphoid depletion were the most evident indicated a deep involvement of th...
متن کاملReproductive failure associated with porcine parvovirus and possible porcine circovirus type 2 co-infection
A 2400-sow multi-site commercial herd experienced an outbreak of reproductive failure characterized by a dramatic increase in mummified fetuses, primarily in primiparous animals. Multiple samples of mummified and stillborn fetuses, placenta, and weak liveborn pigs were submitted to the diagnostic laboratory. Diagnostic testing for porcine parvovirus (PPV) in tissue sections was positive by viru...
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ژورنال
عنوان ژورنال: Animal Models and Experimental Medicine
سال: 2018
ISSN: 2576-2095
DOI: 10.1002/ame2.12009